Metaplastic Breast Cancer

Case Study: Do you need chemotherapy to fight metaplastic breast cancer?

Do you need chemotherapy to fight metaplastic breast cancer? This is a case study of a 70 year old woman with a tumour on her right breast and her decision to have radiation therapy only.

Welcome to the fat neck thyroid club

Welcome to the fat neck thyroid club for underactive thyroid gals....

 

Anxious?  Me?  Never…

Oh well, maybe just a little bit!

This whole chemo rollercoaster has turned my life upside down and inside out.  OK. I am cancer free.  But being cancer free also makes you a nervous crazy wreck.  Every lump, boil, mole or pimple is potential cancer. You start sleeping and thinking about a reoccurrence.  You get googleititus and become a hobby doctor on every aspect of your cancer.  Your friends find you boring as you suddenly start passing off your knowledge on to them and every fag, shot or hot dog they eat – you start to preach about eating “clean”.

Bristol-Myers Squibb NCT01928394 Can you Help Patricia?

Bristol Myers Squibb sponsors a study A Phase 1/2, Open-label Study of Nivolumab Monotherapy or Nivolumab Combined With Ipilimumab in Subjects With Advanced or Metastatic Solid Tumors

Can you help Patricia?

She is a 60 year old cancer patient currently at MDA.  Here is a little bit about her:

Foundation One Study on Metaplastic Breast Cancer

Foundation One has written an excellent study on Metaplastic Breast Caner and Genomic Profiling.

The exact title is a bit of a mouthful but here goes:  Comprehensive Genomic Profiling of Metaplastic Breast Carcinoma By Next Generation Sequencing Reveals Frequent Actionable Genomic Abnormalities and New Routes to Targeted Therapies

Vector Gene Therapy experts?

Vector Gene Therapy?

Are you an expert  - does anyone know someone who can direct us?  One of our girls in the Facebook Metaplastic Breast Cancer Group  needs some help.

 

Please contact me if you can!

 

 

 

Histological subtypes of TNBC including Metaplastic Breast Cancer from ASCO 2014

Metaplastic breast cancer MBC is a histological subtype of TNBC - Triple Negative Breast Cancer.  This short abstract supports the previous article saying that MBC is rare - but not that rare!  This is music to my ears.

 

Out of a group of 502 patients 4% were metaplastic.  That is an increase, as we have seen figures, where on average MBC was 1% of TNBC and 0.01% of all breast cancers.  Increased awareness of MBC is starting to show.   I realise this is a small study but still a positive one...it mentions MBC!!

P13K gene alterations are common in Metaplastic Breast Cancers - ASCO Conference

This is another fantastic article from the ASCO Conference

I love the fact they provide abstracts of the notes for patients and other interested people like us (Thank-You!).

This is a great evaluation of 126 cases of Metaplastic Breast Cancer (MBC) and gene mutations.

I love this quote from the abstract: "The low RRM1 expression rate suggests possible gemcitabine effectiveness".

Is Metaplastic Breast cancer that rare?

Is Metaplastic Breast Cancer that rare?  We all want to know!

I loved this abstract of an article I found from the ASCO conference.  It talks about how Metaplastic Breast Cancer (MBC) is often confused with IDC.

The exact quote is below:

Metaplastic Breast Cancer - links of the day

Metaplastic Breast Cancer

Sorry I have been a bit quiet!  It has been really hectic here and I have creating lots of research and information on Metaplastic Breast Cancer.  Here are some links on cancer and I will try to blog more regularly! XX

Metaplastic Breast Cancer - Mistakes

Metaplastic breast cancer mistakes. This is my tribute to Nicky G and why she died. She fought hard but other factors caused her death. Please read and learn from her. She would have loved that.